MoLife Research Seminar
Ms. Joanna Wilinska, PhD student of Prof. Dr. Detlef Gabel, Prof. of Chemistry, Jacobs University Bremen, Germany
Title of the talk:
Dyes for Eyes: New dyes for vitreoretinal surgery
Abstract: In cases of vitreoretinal interface diseases, such as macular hole or macular pucker, the inner limiting membrane (ILM) or epiretinal membranes (ERM) need to be surgically removed. The challenging step in the surgery is the transparency of ILM and ERM that makes the membranes difficult to identify and to peel without risk of damaging the retina. Only a few vital dyes have been proposed to stain the ILM and ERM and no perfect dye is available that would stain the tissue of interest sufficiently, while being non-toxic and stable in aqueous solution. Therefore, our working group searches for new dyes that would meet the requirements. The study involves not only testing of currently commercially available dyes, but also design and synthesis of brand-new compounds, investigation of their staining ability, toxicity, and stability, including development of new methods and models for staining when necessary.
ALL ARE WELCOME !
Further information by:
Prof. Dr. Detlef Gabel, Professor of Chemistry - Email: d.gabel [at] jacobs-university.de - Tel: +49 421 200-3585 - Link to Homepage: http://www.jacobs-university.de/ses/dgabel